The Wang Lab
at the University of Pennsylvania

focuses on the genetics and genomics of Alzheimer’s disease and other neurodegenerative disorders, and informatics and algorithm development for genome-scale experiments.

Latest News

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2/7/2022
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Carlos Thomas

FILER: a framework for harmonizing and querying large-scale functional genomics knowledge

PNGC is pleased to announce the release of the FILER, a functional genomics repository developed by...
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8/18/2021
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PNGC

Alzheimer’s Disease Variant Portal (ADVP): The Newest Curated Population-specific Alzheimer’s Disease Genetics Resource

By Fernanda Ruiz, NOVA Research Company Alzheimer’s Disease (AD) is a devastating disease that affects more...
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4/13/2021
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Alexis Lerro

PNGC Co-Director Li-San Wang to Present at the 2021 NIH Alzheimer’s Research Summit

The NIH will host their 2021 Alzheimer’s Research Summit April 19-22. This virtual summit will convene...
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Openings

Come Work With Us

The Wang Lab is always looking for qualified people to join our diverse team. We have openings for postdocs, staff, trainees and faculty. Please explore our opportunities below.
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Latest Publications

2025,  
Brain: A Journal of Neurology

Novel modelling approaches to elucidate the genetic architecture of resilience to Alzheimer's disease

Phillips, JM., et al.
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2025,  
Movement Disorders: Official Journal of the Movement Disorder Society

Copy Number Variation and Haplotype Analysis of 17q21.31 Reveals Increased Risk Associated with Progressive Supranuclear Palsy and Gene Expression Changes in Neuronal Cells

Wang, H., et al.
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Featured Projects

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NIAGADS

NIA Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS) is a genetics data repository set up...
Read more " about NIA Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS)"

GCAD

NIA Coordinating Genome Center of Alzheimer’s Disease (GCAD) is a five-year/$10.8M U54 Cooperative Agreement/Specialized Center funded...
Read more " about Genome Center of Alzheimer’s Disease (GCAD)"

ACAD

The Asian Cohort for Alzheimer’s Disease (ACAD) is an international collaboration with the goal of compiling...
Read more " about Asian Cohort for Alzheimer’s Disease (ACAD)"